Make a radical change in your lifestyle and begin to boldly do things which you may previously never have thought of doing, or been too hesitant to attempt.

So many people live within unhappy circumstances and yet will not take the initiative to change their situation because they are conditioned to a life of security, conformity, and conservation, all of which may appear to give one peace of mind, but in reality nothing is more damaging to the adventurous spirit within a man than a secure future.
The very basic core of a man’s living spirit is his passion for adventure.

The joy of life comes from our encounters with new experiences, and hence there is no greater joy than to have an endlessly changing horizon, for each day to have a new and different sun.
If you want to get more out of life, you must lose your inclination for monotonous security and adopt a 'helter-skelter' style of life that will at first appear to you to be crazy.
But once you become accustomed to such a life you will see its full meaning and its incredible beauty.

CONSIDER THE IDEA OF PERMANENT UNCERTAINTY 

Certainty is actually an illusion. Think about it. Is there ever a time when you know for sure how things will unfold?

Even with the best preparation, you can’t control everything in the universe. Job security is subject to industry and company shifts. Relationships transform as people grow and change how they see the world and what they want out of it.

There are never any guarantees, even when you think you have it all figured out. When you don’t know what the future will hold, you’re actually dealing with life as it always is: yours to live and create moment by moment, day by day.

Uncertainty is the only certainty there is, and knowing how to live with insecurity is the only security.
— John Allen Paulos